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Medical Decision Making
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iMPACT3: Internet-Based Development and Administration of Utility Elicitation Protocols

L. A. Lenert, MD

Veterans Administration Healthcare System, San Diego, CA, Department of Medicine, University of California, San Diego, La Jolla, CA, Veterans Medical Research Foundation of San Diego, San Diego, CA

A. Sturley, DrPH

Veterans Medical Research Foundation of San Diego, San Diego, CA

M. E. Watson, PhD

Global Health Outcomes, GlaxoSmithKline, Research Triangle Park, NC

iMPACT3 (Internet Multimedia Preference Assessment Instrument Construction Tool, version 3) is a software development environment that helps researchers build Internet-capable multimedia utility elicitation software programs. The program is a free, openly accessible Web site (http://preferences.ucsd.edu/impact3/asp). To develop a utility elicitation software program using iMPACT3, a researcher selects modular protocol components from a library and custom tailors the components to the details of his or her research protocol. iMPACT3 builds a Web site implementing the protocol and downloads it to the researcher’s computer. In a study of 75 HIV-infected patients, an iMPACT3-generated protocol showed substantial evidence of construct validity and good internal consistency (logic error rates of 4% to 10% and procedural invariance error rates of 10% to 26%, depending on the elicitation method) but only fair 3- to 6-week test-retest reliability (intraclass correlation coefficient = 0.42 to 0.55). Further work may be needed on specific utility assessment procedures, but this study’s results confirm iMPACT3’s feasibility in facilitating the collection of health state utility data.

Key Words: computers • quality of life • cost-effectiveness analysis • decision support systems • utilities

Medical Decision Making, Vol. 22, No. 6, 464-474 (2002)
DOI: 10.1177/0272989X02238296
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