This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Badia, X. Articles by Kind, P. Search for Related Content PubMed PubMed Citation Articles by Badia, X. Articles by Kind, P. Social Bookmarking                         What's this?

A Comparison of United Kingdom and Spanish General Population Time Trade-off Values for EQ-5D Health States

Catalan Institute of Public Health, Barcelona, Spain

Montserrat Roset, BSc

Catalan Institute of Public Health, Barcelona, Spain

Michael Herdman, MSc

Catalan Institute of Public Health, Barcelona, Spain

Paul Kind, PhD

Catalan Institute of Public Health, Barcelona, Spain

Few studies have compared preference values for health states obtained in different countries. The present study compared Spanish and United Kingdom (UK) time trade-off values for EuroQol-5D health states. The same preference elicitation protocol was followed in both countries. Differences in values for 43 health states rated directly were analyzed using t tests, and regression coefficients generated by random effects modeling were compared by aggregating the 2 value sets and using dummy variables to analyze country effect by dimension and level of severity. For the milder health states, Spanish and UK value assignation was similar; for intermediate health states, Spanish values were both higher and lower than UK values, whereas for health states worse than death, UK values were generally higher than Spanish values. There were statistically significant differences (P < 0.01) in values for 34.9% of health states rated directly, and some preference reversals between countries. UK raters ascribed greater importance to dimensions of pain/discomfort and anxiety/depression, whereas Spanish raters placed more importance on functional dimensions of mobility and self-care. Further analysis is required to determine how these differences affect cost-effectiveness and cost-utility analyses.

Key Words: EQ-5D • health states • preference values • United Kingdom • Spain • comparison

Medical Decision Making, Vol. 21, No. 1, 7-16 (2001)
DOI: 10.1177/0272989X0102100102


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				K. U. Wittrup-Jensen, J. Lauridsen, C. Gudex, and K. M. Pedersen Generation of a Danish TTO value set for EQ-5D health states Scand J Public Health, July 1, 2009; 37(5): 459 - 466. [Abstract] [PDF]

				M. Zlowodzki, O. Brink, J. Switzer, S. Wingerter, J. Woodall Jr, B. A. Petrisor, P. J. Kregor, D. R. Bruinsma, and M. Bhandari The effect of shortening and varus collapse of the femoral neck on function after fixation of intracapsular fracture of the hip: A MULTI-CENTRE COHORT STUDY J Bone Joint Surg Br, November 1, 2008; 90-B(11): 1487 - 1494. [Abstract] [Full Text] [PDF]

				I. Olivieri, S. de Portu, C. Salvarani, A. Cauli, E. Lubrano, A. Spadaro, F. Cantini, M. S. Cutro, A. Mathieu, M. Matucci-Cerinic, et al. The psoriatic arthritis cost evaluation study: a cost-of-illness study on tumour necrosis factor inhibitors in psoriatic arthritis patients with inadequate response to conventional therapy Rheumatology, November 1, 2008; 47(11): 1664 - 1670. [Abstract] [Full Text] [PDF]

				Nan Luo, J. A. Johnson, J. W. Shaw, and S. J. Coons A Comparison of EQ-5D Index Scores Derived from the US and UK Population-Based Scoring Functions Med Decis Making, May 1, 2007; 27(3): 321 - 326. [Abstract] [PDF]

				R. Lilford, A. Girling, D. Braunholtz, W. Gillett, J. Gordon, C. A. Brown, and A. Stevens Cost-Utility Analysis When Not Everyone Wants the Treatment: Modeling Split-Choice Bias Med Decis Making, January 1, 2007; 27(1): 21 - 26. [Abstract] [PDF]

				N. Luo, Q. Wang, D. Feeny, G. Chen, S.-C. Li, and J. Thumboo Measuring Health Preferences for Health Utilities Index Mark 3 Health States: A Study of Feasibility and Preference Differences among Ethnic Groups in Singapore Med Decis Making, January 1, 2007; 27(1): 61 - 70. [Abstract] [PDF]

				L. M. Lamers, P. F. M. Stalmeier, P. F. M. Krabbe, and J. J. V. Busschbach Inconsistencies in TTO and VAS Values for EQ-5D Health States Med Decis Making, March 1, 2006; 26(2): 173 - 181. [Abstract] [PDF]

				M. J. Calvert, N. Freemantle, G. Yao, J. G.F. Cleland, L. Billingham, J.-C. Daubert, S. Bryan, and on behalf of the CARE-HF Investigators Cost-effectiveness of cardiac resynchronization therapy: results from the CARE-HF trial Eur. Heart J., December 2, 2005; 26(24): 2681 - 2688. [Abstract] [Full Text] [PDF]

				A. Gringeri, L. G. Mantovani, L. Scalone, and P. M. Mannucci Cost of care and quality of life for patients with hemophilia complicated by inhibitors: the COCIS Study Group Blood, October 1, 2003; 102(7): 2358 - 2363. [Abstract] [Full Text] [PDF]