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Medical Decision Making
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Construct Validities of the Quality of Well-Being Scale and the MOS-HIV-34 Health Survey for HIV-infected Patients

Tom E. Hughes, PhD

Robert M. Kaplan, PhD

Stephen Joel Coons, PhD

Jolaine R. Draugalis, PhD

Jeffrey A. Johnson, MSc

Thomas L. Patterson, PhD

This research assessed the construct validities of two health-related quality-of-life in struments: the Quality of Well-Being Scale (QWB) and the Medical Outcomes Study 34-item HIV Health Survey (MOS-HIV-34). A sample of 100 adult male, HIV-infected patients, across six HIV disease classifications, was used as subjects. Four convergent validity measures of health-related quality of life were used: CD4 cell counts, beta-2 microglobulin levels, disease classification, and age. All convergent validity measures were significant for the QWB. Forty percent of the convergent validity com parisons with the MOS-HIV-34 were statistically significant. Because the two measures provide different perspectives on health-related quality of life, both instruments appear to be useful in measuring health-related quality of life in this patient population. Key words: HIV; quality of life; quality of well-being scale; construct validity. (Med Decis Making 1997;17:439-446)

Medical Decision Making, Vol. 17, No. 4, 439-446 (1997)
DOI: 10.1177/0272989X9701700409
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