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Patency Results of Percutaneous and Surgical Revascularization for Femoropopliteal Arterial Disease

John B. Wong, MD

Magruder C. Donaldson, MD

Michael F. Meyerovitz, MD

Donald P. Harrington, MD

To estimate the patency results of percutaneous transluminal angioplasty and bypass surgery in the treatment of femoropopliteal arterial disease, a Medlars search of the English-language medical literature was performed. Inclusion required that studies 1) report original data, 2) report patency with a life table or Kaplan-Meier analysis with the number at risk or standard errors, 3) define patency as hemodynamic improvement, 4) report the distribution of co variates, and 5) not duplicate other published material. Using a method based on the pro portional-hazards model and the actuarial life-table approach, the results were adjusted for differences in case-mix of the study populations and patency was predicted for subgroups at various levels of risk for failure. The unadjusted pooled life tables yielded five-year pa tencies of 45% (± 2%) for angioplasty, 73% (± 2%) for bypass surgery using a vein graft, and 49% ( ± 3%) for bypass surgery using a polytetrafluoroethylene graft. Adjusted five- year primary patencies after angioplasty varied from 12% to 68%, the best results being for patients with claudication and stenotic lesions. Adjusted five-year primary patencies after surgery varied from 33% to 80%, the best results being for saphenous vein bypass performed for claudication. The authors conclude that pooling life-table data without adjustment for covariates can be misleading. Indication, lesion type, vein graft availability, and site of the distal graft anastomosis need to be considered in predicting patency results of revascular ization for femoropopliteal arterial disease. Key words: arteries, femoral; arteries, popliteal; arteries, transluminal angioplasty; arteries, surgery; review; meta-analysis. (Med Decis Mak ing 1994;14:71-81)

Medical Decision Making, Vol. 14, No. 1, 71-81 (1994)
DOI: 10.1177/0272989X9401400109


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